Private Practice Infectious Disease

(ISSN: 2770-4629) Open Access Journal
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PPID, Volume 2, Issue 3 (September 2022)
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PPID 2022, 2(3), 9; doi: 10.55636/ppid2030009
Received: 31 May 2022 / Revised: 26 Aug 2022 / Accepted: 20 Jun 2022 / Published: 30 Sep 2022
It has been twenty-five years since antiretroviral therapy (ART) for human immunodeficiency virus (HIV) became available. Treatment has evolved substantially over these decades to become highly effective and produce substantial improvements in morbidity and mortality for people with HIV. The standard of care
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It has been twenty-five years since antiretroviral therapy (ART) for human immunodeficiency virus (HIV) became available. Treatment has evolved substantially over these decades to become highly effective and produce substantial improvements in morbidity and mortality for people with HIV. The standard of care has been three-drug regimens (3DRs) which include three drugs active against HIV, occasionally with a fourth drug added as a booster agent. Efforts to provide potentially safer or more convenient treatment regimens for people with HIV have served as the impetus to relook at two drug regimens (2DRs). Several studies have led to the establishment of 2DRs as real options for many patients. This review summarizes clinical data for the established 2DRs and explores some of the remaining questions and concerns about these regimens. Full article
PPID 2022, 2(3), 10; doi: 10.55636/ppid2030010
Received: 27 May 2022 / Revised: 7 Jul 2022 / Accepted: 12 Jul 2022 / Published: 30 Sep 2022
The formulation of a rapid differential diagnosis can be aided by categorizing common clinical syndromes. Our review article presents a case of a fever/jaundice presentation with a review of its most common causes. Cogent points for work up and treatment of each diagnosis
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The formulation of a rapid differential diagnosis can be aided by categorizing common clinical syndromes. Our review article presents a case of a fever/jaundice presentation with a review of its most common causes. Cogent points for work up and treatment of each diagnosis will be presented as well. Full article
PPID 2022, 2(3), 11; doi: 10.55636/ppid2030011
Received: 16 Jun 2022 / Revised: 26 Aug 2022 / Accepted: 29 Aug 2022 / Published: 30 Sep 2022
Introduction. The Cardiobacterium species is a pleomorphic Gram-negative bacterium discovered in 1964 and is part of the HACEK (Haemophilus, Aggregatibacter, Cardiobacterium, Eikenella, and Kingella) group of organisms known to cause endocarditis. It has low virulence and
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Introduction. The Cardiobacterium species is a pleomorphic Gram-negative bacterium discovered in 1964 and is part of the HACEK (Haemophilus, Aggregatibacter, Cardiobacterium, Eikenella, and Kingella) group of organisms known to cause endocarditis. It has low virulence and can also cause dacryocystitis, septicemia and abdominal abscess. We report a patient with C. hominis prosthetic joint infection in the absence of definitive endocarditis. Case Report. A 57-year-old man presented to his orthopedic surgeon 17 months after left total knee arthroplasty with a 4–5-day history of left knee pain following yard work. He had an aortic valve replacement in 2003, mitral valve repair in 2006 and bovine aortic valve replacement in 2019 (12 months previously). Aspirate of knee joint fluid was grossly cloudy. Two of two preoperative blood cultures revealed Cardiobacterium species after 4 days’ incubation. He was initially treated with intravenous vancomycin plus piperacillin/tazobactam followed by 6 weeks of parenteral ceftriaxone followed by five months of oral cefdinir. Patient is infection-free 6 months after completion of antimicrobial therapy. Discussion. Cardiobacterium hominis is a slow-growing, fastidious, capnophilic, Gram-negative bacillus commonly found in normal oral and upper respiratory flora. Google Scholar™ and PubMed® searches were conducted and this is the first reported case of prosthetic joint infection due to Cardiobacterium hominis. We found three previously reported cases of C. hominis pyogenic arthritis: one patient with native knee pyogenic arthritis, one patient with cervical spondylodiscitis and one patient with lumbar spondylodiscitis and epidural abscess. Two of these three patients had TEE-documented infective endocarditis and one had a bioprosthetic aortic valve without evident vegetation on TEE. Our patient had a bioprosthetic aortic valve without TEE evidence of endocarditis. C. hominis should be added to the list of organisms that can cause bacteremically spread prosthetic joint infection. Full article
PPID 2022, 2(3), 8; doi: 10.55636/ppid2030008
Received: 12 Dec 2021 / Revised: 1 Jun 2022 / Accepted: 2 Jun 2022 / Published: 30 Jun 2022
The formulation of a rapid differential diagnosis can be aided by categorizing common clinical syndromes. Our review article presents a case of a “lung/brain” syndrome with a review of it’s most common causes. Cogent points for work up and treatment of each diagnosis
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The formulation of a rapid differential diagnosis can be aided by categorizing common clinical syndromes. Our review article presents a case of a “lung/brain” syndrome with a review of it’s most common causes. Cogent points for work up and treatment of each diagnosis will be presented as well. Full article

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